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Our Medical Review

By Dr. Terrance Owen, PhD, MBA

To request the original white papers document, please scroll to the bottom of the page and fill out the form. The following below is a summarized version of Dr Terrance Owen's report.

Executive Summary

The white paper reviews the efficacy and safety of Oleavicin, a treatment for cold sores caused by Herpes simplex I (HSV-1). While no formal clinical studies have been conducted, anecdotal reports support the claims of its effectiveness. Scientific literature corroborates the antimicrobial properties of olive leaf extract (OLEx), a key component of Oleavicin. Users have reported reduced healing times without side effects. Compared to other treatments like docosanol, Oleavicin is cost-effective and safer.

Introduction

Oleavicin is a topical gel made from olive leaf extract and other natural ingredients, marketed for treating cold sores, canker sores, and minor skin irritations. Cold sores are prevalent, especially in older adults, and there is no cure for HSV-1. Canker sores have various causes, and anecdotal evidence suggests Oleavicin can provide relief.

Historical Use of Olive Tree

Olive trees have been used for medicinal purposes since biblical times. Olive leaf extracts are known for their antimicrobial properties against bacteria, viruses, fungi, and parasites. Key components like oleuropein have shown antibacterial, antiviral, and antifungal activities.

Oleuropein Pharmacology

Oleuropein (Ole) has various pharmacological properties, including anti-inflammatory, anti-cancer, neuroprotective, and hypoglycemic effects. Most studies have been conducted in vitro or on animals, with limited human clinical trials. No Oleavicin products were tested on animals.

Antimicrobial Activity of OLEx

OLEx has demonstrated activity against various viruses, although specific studies on HSV-1 are lacking. Ingredients in Oleavicin, such as Aloe vera, glucose oxidase, St. John’s wort, and propolis, have established antimicrobial properties and contribute to its effectiveness against cold sores.

Testimonials

Anecdotal reports from users, particularly on Amazon.com, indicate that Oleavicin reduces cold sore healing time by 2 to 3 days without side effects. Some negative reviews mentioned issues like packaging or shipping.

Composition

Active ingredients in Oleavicin include allantoin, St. John’s wort extract, olive fruit oil, and propolis extract. Other components like Aloe vera, glucose oxidase, glycerin, and menthol contribute to its antimicrobial and soothing properties.

Safety

Oleavicin is registered with Health Canada as a safe natural product for minor skin wounds and irritations. There are no reported side effects, although allergic reactions to ingredients are possible. Usage warnings include avoiding contact with eyes and not sharing the product to prevent infection spread.

Application Regimen

Oleavicin should be applied 1 to 4 times daily for up to 7 days to the affected area.

Other Treatments for HSV-1

Common antiviral agents like acyclovir and docosanol show limited efficacy and potential side effects. Docosanol (Abreva) shortens healing time by 18 hours compared to placebo but is more expensive than Oleavicin during the time of this report was produced.

Stability and Shelf Life

Oleavicin has a shelf life of 24 months.

References and Author

The white paper includes extensive references to scientific studies and literature. Dr. Terrance Owen has a background in biochemistry, biotechnology, and pharmaceuticals, with significant experience in infection control and medical services.

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